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Christina L van Broekhoven Selected Research

nitrilotriacetic acid ditetradecylamine

10/2005The novel chelator lipid 3(nitrilotriacetic acid)-ditetradecylamine (NTA(3)-DTDA) promotes stable binding of His-tagged proteins to liposomal membranes: potent anti-tumor responses induced by simultaneously targeting antigen, cytokine and costimulatory signals to T cells.
3/2002A novel approach for modifying tumor cell-derived plasma membrane vesicles to contain encapsulated IL-2 and engrafted costimulatory molecules for use in tumor immunotherapy.

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Christina L van Broekhoven Research Topics

Disease

4Neoplasms (Cancer)
10/2005 - 03/2002
2Mastocytoma
10/2005 - 03/2002
2Melanoma (Melanoma, Malignant)
11/2004 - 06/2004

Drug/Important Bio-Agent (IBA)

4VaccinesIBA
10/2005 - 03/2002
3AntigensIBA
10/2005 - 06/2004
2CytokinesIBA
10/2005 - 03/2002
2Cancer VaccinesIBA
10/2005 - 03/2002
2Interleukin-2 (IL2)IBA
10/2005 - 03/2002
2Proteins (Proteins, Gene)FDA Link
10/2005 - 03/2002
2nitrilotriacetic acid ditetradecylamineIBA
10/2005 - 03/2002
1Interleukin-12 (IL 12)IBA
10/2005
1LipidsIBA
10/2005
1Chelating AgentsIBA
10/2005
1Liposomes (Liposome)IBA
06/2004
1ChemokinesIBA
06/2004
1Neoplasm Antigens (Tumor Antigens)IBA
06/2004
1His-His-His-His-His-His ((His)6)IBA
03/2002
1B7 AntigensIBA
03/2002

Therapy/Procedure

3Immunotherapy
11/2004 - 03/2002